Tirzepatide is a once-weekly injectable medication that mimics two hormones—GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide)—which help regulate blood sugar, slow digestion, and reduce appetite, supporting significant weight loss.

• Appetite Suppression: Tirzepatide mimics two naturally occurring hormones — GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide) — that help regulate appetite and metabolism. This dual-action approach reduces hunger, increases feelings of fullness, and leads to reduced calorie intake.
• Slowed Gastric Emptying: Tirzepatide delays the emptying of food from the stomach, which prolongs the feeling of fullness after meals. This helps reduce snacking and portion sizes throughout the day.
• Blood Sugar Regulation: By enhancing insulin secretion when blood sugar is elevated and decreasing glucagon (a hormone that raises blood sugar), tirzepatide helps stabilize blood sugar levels. This reduces insulin resistance and helps prevent hunger spikes caused by fluctuations in blood sugar.
• Lower Caloric Intake: With less frequent hunger and improved satiety, individuals taking tirzepatide tend to eat less overall — leading to a calorie deficit that promotes consistent weight loss.
• Part of a Holistic Plan: Tirzepatide is most effective when combined with a reduced-calorie diet, regular physical activity, and behavioral support. It is not a quick fix, but rather a valuable tool within a medically supervised weight management program.

Typically, tirzepatide is part of a comprehensive weight management plan that includes a reduced-calorie diet and increased physical activity. It’s not a stand-alone treatment and should be prescribed and monitored by a healthcare professional to ensure safe and effective use.

Yes, tirzepatide is FDA-approved for weight loss. In 2024, the FDA approved tirzepatide (brand name Zepbound) specifically for chronic weight management in adults with obesity or those who are overweight and have at least one weight-related condition (such as high blood pressure, type 2 diabetes, or high cholesterol). This approval represents a major step forward in the treatment of obesity.

Tirzepatide has shown the ability to support significant weight loss when combined with a healthy diet and regular physical activity. Clinical studies have found that losing just 5% to 10% of body weight can lead to meaningful improvements in overall health, including reduced risk for heart disease and better metabolic function.

While tirzepatide can be highly effective for weight loss and blood sugar management, it may also cause unwanted side effects. Not everyone will experience these side effects, but if they do occur, some may require medical attention.

Contact your healthcare provider immediately if you experience any of the following side effects while taking tirzepatide:

Common Side Effects

• Nausea
• Vomiting
• Diarrhea
• Constipation
• Decreased appetite
• Indigestion or upset stomach
• Abdominal pain or discomfort
• Fatigue
• Dizziness
• Belching or gas

Less Common but Possible Side Effects

• Headache
• Injection site reactions (redness, swelling, or itching)
• Gastroesophageal reflux (heartburn)
• Hair thinning or shedding (reported anecdotally, not confirmed in studies)

Serious Side Effects (Require immediate medical attention)

• Pancreatitis (inflammation of the pancreas): symptoms include severe abdominal pain, nausea, vomiting
• Gallbladder problems, including gallstones
• Kidney problems, especially if dehydration occurs from vomiting/diarrhea
• Severe gastrointestinal issues, like gastroparesis (delayed stomach emptying)
• Allergic reactions: rash, itching, swelling, trouble breathing
• Hypoglycemia (low blood sugar), especially when used with other diabetes medications
• Thyroid tumors, including medullary thyroid carcinoma (MTC) – observed in animal studies (not confirmed in humans), but tirzepatide is not recommended for those with a personal or family history of MTC or MEN 2 (Multiple Endocrine Neoplasia syndrome type 2)

Adults with a BMI of 30 or higher, or a BMI of 27 or higher with at least one weight-related condition (like type 2 diabetes, high blood pressure, or high cholesterol), may be good candidates.

Tirzepatide is a prescription medication primarily used to manage type 2 diabetes and support long-term weight loss in individuals with obesity or overweight. It is marketed under the brand name Mounjaro and is known for its dual-action effectiveness in both blood sugar control and weight reduction.

Tirzepatide is a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist. This unique combination mimics the effects of two naturally occurring incretin hormones. It helps regulate blood sugar by enhancing insulin secretion when glucose levels are high and reducing glucagon production. Tirzepatide also slows gastric emptying and suppresses appetite, which contributes to reduced calorie intake and meaningful weight loss.

Tirzepatide has shown impressive results for weight loss in both clinical trials and real-world settings. In the SURMOUNT-1 clinical trial, participants taking tirzepatide lost up to 22.5% of their body weight after 72 weeks of treatment. This translates to an average weight loss of about 52 pounds, with many individuals experiencing even greater results depending on their dose and adherence to a healthy lifestyle.

Most patients lose 15% to 22% of their body weight after approximately 72 weeks of consistent treatment, depending on dosage and lifestyle changes.

Tirzepatide is not a fast solution for weight loss. It usually takes several weeks to months of treatment to achieve weight loss goals. It is prescribed for individuals dealing with obesity as part of a complete weight management plan that includes lifestyle changes such as a healthy diet and regular exercise.

Some people may notice a small amount of weight loss in the first week, mainly due to reduced appetite and fluid loss, but significant weight loss typically occurs over several weeks to months.

Most users report reduced hunger and cravings due to tirzepatide’s impact on appetite-regulating hormones.

Tirzepatide is typically started at 2.5 mg once weekly and gradually increased to a maintenance dose of 5 mg to 15 mg, depending on your response and tolerance.

You can take tirzepatide at any time of day, with or without food. It should be taken on the same day each week for consistency.

Tirzepatide is injected subcutaneously (under the skin) in the stomach, thigh, or upper arm. Rotate injection sites weekly to prevent irritation.

Moderate alcohol use is generally safe, but excessive drinking can increase the risk of side effects like low blood sugar and gastrointestinal issues. Always consult your healthcare provider.

Not necessarily. Some patients may need long-term use to maintain weight loss, while others may transition off after reaching their goals. Discontinuation should always be discussed with a healthcare provider.

Treatment duration depends on your weight loss goals, progress, and health status. Many people stay on tirzepatide for 12 to 18 months or longer under medical supervision.

Appetite reduction and initial weight loss may begin within the first few weeks, but more significant results are typically seen after 8 to 12 weeks of consistent use. But, it is important to understand some of the variations between patients response to tirzepatide. See some of the varying factors below:

• Initial Changes: Some people may start to observe initial weight changes within a few weeks of beginning tirzepatide treatment.
• Significant Progress: Achieving more substantial weight loss typically requires several weeks to months of treatment. The rate of weight loss can be influenced by various factors, including the individual’s starting weight, diet, exercise habits, and overall lifestyle.
• Patience and Consistency: Reaching and maintaining a healthy weight is a gradual process, so patience is essential. Patients should adhere to their healthcare provider’s guidance and maintain consistent treatment to optimize the benefits of tirzepatide for weight loss.
• Individual Variations: It’s important to remember that responses to tirzepatide can vary among individuals. Some may see quicker results, while others might take longer to achieve significant changes.

Some weight regain is possible if the medication is stopped without maintaining healthy habits. It’s important to have a long-term lifestyle plan in place before stopping.

Tirzepatide should be used along with a balanced diet, regular physical activity, and behavioral changes for best results.

Yes. A lower-calorie, nutrient-rich diet and increased physical activity are strongly recommended to support tirzepatide’s effectiveness.

• Healthy Eating: Focus on a balanced, nutrient-rich diet that includes fruits, vegetables, lean proteins, whole grains, and healthy fats. A well-rounded diet supports your weight loss goals and overall health while using tirzepatide.
• Portion Control: Tirzepatide helps suppress appetite, but portion control is still key. Being mindful of how much you eat can significantly enhance your results.
• Foods to Avoid: Cut back on or eliminate high-calorie, sugary, and fatty foods, including processed snacks and sweetened beverages. These can interfere with tirzepatide’s effectiveness and slow your progress.
• Regular Exercise:  Engage in consistent physical activity, such as walking, strength training, or cardio. Exercise complements tirzepatide's effects by boosting metabolism and promoting long-term weight management.
• Hydration: Drink plenty of water throughout the day. Staying hydrated helps control hunger, supports digestion, and enhances the benefits of tirzepatide.
• Medical Supervision: Tirzepatide should always be used under the care of a qualified healthcare provider. Regular check-ins allow for safe monitoring, dose adjustments, and personalized support tailored to your progress.

Some benefits of tirzepatide include:

• Dual-action mechanism: Tirzepatide targets both GLP-1 and GIP receptors, making it more effective for weight loss than medications that only target GLP-1 (like semaglutide).
• Greater average weight loss: Clinical studies (such as the SURMOUNT trials) show that tirzepatide may lead to more significant weight loss than many other prescription weight loss drugs.
• Improved metabolic control: In addition to weight loss, tirzepatide improves blood sugar levels, cholesterol, and triglyceride levels.
• Once-weekly dosing: Like semaglutide, tirzepatide is administered just once a week, offering convenience for patients.
• Potential cardiovascular and kidney benefits: Ongoing research suggests tirzepatide may reduce the risk of heart and kidney disease, especially in people with type 2 diabetes.

Some risks associated with tirzepatide include:

• Gastrointestinal side effects: Nausea, vomiting, diarrhea, and constipation are common, especially when starting or increasing dosage.
• Injection-based medication: Unlike oral weight loss drugs, tirzepatide is a subcutaneous injection, which may not be ideal for all patients.
• Cost and insurance coverage: Tirzepatide can be expensive and is not always covered by insurance for weight loss unless prescribed for type 2 diabetes.
• Long-term data still emerging: While early studies are promising, tirzepatide is relatively new, and long-term safety data (especially for weight loss use) is still being collected.
• Not suitable for everyone: People with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2 should avoid GLP-1/GIP medications like tirzepatide.

Tirzepatide may slow the absorption of oral medications. Always inform your provider about all medications you’re taking to avoid interactions.

At this time, our tirzepatide weight loss program is self-pay only, and we do not accept insurance for tirzepatide treatments. The cost of the program includes weekly injections and ongoing support, but you’ll need to cover the fees independently.

Yes, you can travel with tirzepatide, but it’s important to follow proper storage guidelines to maintain the medication’s effectiveness:

• Refrigeration is ideal: Tirzepatide (brand name Mounjaro) should be stored in the refrigerator between 36°F and 46°F (2°C to 8°C) when not in use.
• Short-term travel flexibility: Tirzepatide can be kept at room temperature (up to 86°F or 30°C) for up to 21 days. If you're traveling for a short time, you may not need to keep it refrigerated.
• Use an insulated travel case: If you're flying or expect to be in warm environments, carry your pen in an insulated cooler or medical travel case with a cold pack—but don’t freeze it.
• Keep it in your carry-on: When flying, always keep your tirzepatide in your carry-on luggage, not checked baggage, to avoid temperature extremes and ensure accessibility.
• Label and prescription: Carry the medication in its original packaging with your prescription label, and bring a copy of your prescription in case you're questioned by airport security or customs.

If you’re planning an extended trip or international travel, check storage guidelines in advance and consult your healthcare provider for additional recommendations.

Yes. Tirzepatide should be stored in the refrigerator, but it can be kept at room temperature (up to 86°F) for up to 21 days if needed. Use a cold pack when traveling, especially if the trip is long or temperatures are high.